A novel autism-associated KCNB1 mutation dramatically slows Kv2.1 potassium channel activation, deactivation and inactivation
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DOI: 10.3389/fncel.2024.1438101
Abstract: KCNB1, on human chromosome 20q13.3, encodes the alpha subunit of the Kv2.1 voltage gated potassium channel. Kv2.1 is ubiquitously expressed throughout the brain and is critical in controlling neuronal excitability, including in the hippocampus and… read more here.
Keywords: kv2; channel activation; autism; potassium channel ... See more keywords