On the activation and deactivation pathways of the Lck kinase domain: a computational study
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DOI: 10.1007/s10822-019-00204-0
Abstract: Here we report the description of the conformational pathways connecting the Lck active and inactive states by means of all-atoms molecular dynamics simulations coupled to an enhancing sampling methodology. By such an approach, we describe… read more here.
Keywords: activation deactivation; kinase; deactivation pathways; lck kinase ... See more keywords