Identification of Adenosine Deaminase Inhibitors by Metal‐binding Pharmacophore Screening
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DOI: 10.1002/cmdc.202000271
Abstract: Adenosine deaminase (ADA) is a human mononuclear Zn2+ metalloenzyme that converts adenosine to inosine. ADA is a validated drug target for cancer, but there has been little recent work on the development of new therapeutics… read more here.
Keywords: deaminase inhibitors; inhibitors metal; metal binding; identification adenosine ... See more keywords