Pd-Catalyzed Dearomative Carboxylation of Indolylmethanol Derivatives.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b03337
Abstract: By using a new catalytic system (PdCl2[P( n-Bu)3]2 in combination with ZnEt2), various 3-indolylmethanol derivatives were successfully carboxylated with CO2 (1 atm) via dearomatization of the indole nucleus, affording 3-methyleneindoline-2-carboxylates. In contrast, carboxylation of 2-indolylmethanol… read more here.
Keywords: carboxylation indolylmethanol; indolylmethanol derivatives; catalyzed dearomative; dearomative carboxylation ... See more keywords