Divergent and Enantioselective Synthesis of Three Types of Chiral Polycyclic N‑Heterocycles via Copper-Catalyzed Dearomative Cyclization
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DOI: 10.1021/acscentsci.5c00248
Abstract: Significant advancements have been made in the catalytic asymmetric dearomatization of indoles for constructing valuable chiral polycyclic N-heterocycles. However, the asymmetric dearomative cyclopropanation of indoles continues to pose a formidable challenge. Furthermore, the diverse transformations… read more here.
Keywords: dearomative cyclopropanation; divergent enantioselective; asymmetric dearomative; synthesis ... See more keywords
Asymmetric dearomative cyclopropanation of naphthalenes to construct polycyclic compounds
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DOI: 10.1039/d2sc04509e
Abstract: Catalytic asymmetric dearomatization (CADA) reactions is an important synthetic method for constructing enantioenriched complex cyclic systems from simple aromatic feedstocks. However, the CADA reactions of nonactivated arenes, such as naphthalenes and benzenes, have been far… read more here.
Keywords: cyclopropanation naphthalenes; naphthalenes construct; cyclopropanation; polycyclic compounds ... See more keywords