Multiple roles of caspase‐8 in cell death, inflammation, and innate immunity
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3mr0420-305r
Abstract: Caspase‐8 is an apical caspase involved in the programmed form of cell death called apoptosis that is critically important for mammalian development and immunity. Apoptosis was historically described as immunologically silent in contrast to other… read more here.
Keywords: cell death; death; caspase cell; death inflammation ... See more keywords
Cell Death and Inflammation - A Vital but Dangerous Liaison.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in immunology"
DOI: 10.1016/j.it.2019.03.006
Abstract: The immune system has developed multiple ways to fight infection. Yet, it is constantly tasked with overcoming newly developing pathogenic mechanisms of resistance to host immunity. In most mammals, the stimulation of both innate and… read more here.
Keywords: death inflammation; death; ripk1 ripk3; cell death ... See more keywords
Death by inflammation: drug makers chase the master controller
Sign Up to like & getrecommendations! Published in 2019 at "Nature Biotechnology"
DOI: 10.1038/s41587-019-0023-4
Abstract: Companies are now looking at RIPK1 inhibitors for diseases like neurodegeneration and even cancer. read more here.
Keywords: chase master; death inflammation; makers chase; inflammation drug ... See more keywords
Deubiquitinases in cell death and inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Journal"
DOI: 10.1042/bcj20210735
Abstract: Apoptosis, pyroptosis, and necroptosis are distinct forms of programmed cell death that eliminate infected, damaged, or obsolete cells. Many proteins that regulate or are a part of the cell death machinery undergo ubiquitination, a post-translational… read more here.
Keywords: cell death; deubiquitinases cell; death; death inflammation ... See more keywords