A bacterial effector manipulates host lysosomal protease activity–dependent plasticity in cell death modalities to facilitate infection
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2406715122
Abstract: Significance Mammalian hosts coordinate various cell death pathways as part of defense system against pathogens including Mycobacterium tuberculosis (Mtb), which causes tuberculosis featured with lung inflammation and necrosis. However, how Mtb manipulates host molecular switches… read more here.
Keywords: protease; cell; death modalities; manipulates host ... See more keywords
Cell Death Modalities in Therapy of Melanoma
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DOI: 10.3390/ijms26083475
Abstract: Melanoma, one of the most lethal cancers, demands urgent and effective treatment strategies. However, a successful therapeutic approach requires a precise understanding of the mechanisms underlying melanoma initiation and progression. This review provides an overview… read more here.
Keywords: modalities therapy; therapy melanoma; melanoma; death modalities ... See more keywords