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1
Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-4703
Abstract: Background: Debio 1143 is an oral antagonist of IAPs, currently in clinical development, which sensitizes tumor cells to radiation- or chemotherapy-induced apoptosis. IAPs inhibitors modulate NF-κB signaling and drive the expression of genes relevant for…
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Keywords:
inhibitors vitro;
anti;
debio 1143;
antagonist ... See more keywords
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1
Published in 2020 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2020-116
Abstract: Debio 1143 plus chemoradiotherapy improved head and neck squamous cell carcinoma disease control.
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Keywords:
antagonist debio;
1143 enhances;
debio;
chemoradiotherapy ... See more keywords