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Enhanced Survival of High-Risk Medulloblastoma-Bearing Mice after Multimodal Treatment with Radiotherapy, Decitabine, and Abacavir

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23073815

Abstract: Children with high-risk SHH/TP53-mut and Group 3 medulloblastoma (MB) have a 5-year overall survival of only 40%. Innovative approaches to enhance survival while preventing adverse effects are urgently needed. We investigated an innovative therapy approach… read more here.

Keywords: tp53 mut; therapy; shh tp53; bearing mice ... See more keywords