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Published in 2017 at "Leukemia"
DOI: 10.1038/leu.2017.99
Abstract: Epigenetic loss of the RNA decapping enzyme NUDT16 mediates C-MYC activation in T-cell acute lymphoblastic leukemia
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Keywords:
loss rna;
nudt16 mediates;
epigenetic loss;
decapping enzyme ... See more keywords
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Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-45083-5
Abstract: Eukaryotic mRNAs are modified at their 5′ end early during transcription by the addition of N7-methylguanosine (m7G), which forms the “cap” on the first 5′ nucleotide. Identification of the 5′ nucleotide on mRNA is necessary…
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Keywords:
enzyme dcps;
yeast scavenger;
rna;
scavenger decapping ... See more keywords
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1
Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa337
Abstract: Abstract Most eukaryotic mRNAs harbor a characteristic 5′ m7GpppN cap that promotes pre-mRNA splicing, mRNA nucleocytoplasmic transport and translation while also protecting mRNAs from exonucleolytic attacks. mRNA caps are eliminated by Dcp2 during mRNA decay,…
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Keywords:
dcp2 decapping;
dcp2;
pby1 direct;
direct partner ... See more keywords
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Published in 2018 at "Oncology letters"
DOI: 10.3892/ol.2018.8730
Abstract: Processing bodies (P-bodies) are one of the most well understood types of RNA granules, and are associated with a variety of diseases, including cancer. mRNA-decapping enzyme 1a (DCP1a), which may be used as a marker…
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Keywords:
dcp1a;
carcinoma;
colorectal carcinoma;
mrna decapping ... See more keywords