Synthesis of quinazolin-4(3H)-ones via electrochemical decarboxylative cyclization of α‑keto acids with 2-aminobenzamides
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Catalysis"
DOI: 10.1016/j.mcat.2020.111345
Abstract: Abstract Herein, an environmentally benign electrochemical protocol has been disclosed for the synthesis of quinazolin-4(3H)-one derivatives from readily available α‑keto acids and 2-aminobenzamides. This decarboxylative cyclization process proceeds conveniently in the absence of any homogeneous… read more here.
Keywords: synthesis quinazolin; decarboxylative cyclization; acids aminobenzamides; keto acids ... See more keywords
Novel synthesis of tetrahydro-1H-pyrrolo[1,2-a]imidazol-2-ones via decarboxylative cyclization reaction of α-amino acids and α-ketoamides
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DOI: 10.1016/j.tetlet.2016.12.079
Abstract: An efficient and practical method was developed for the synthesis of tetrahydro-1H-pyrrolo[1,2-a]imidazol-2-ones based on the decarboxylative cyclization reaction of α-ketoamides and proline. In most cases, tetrahydro-1H-pyrrolo[1,2-a]imidazol-2-ones were obtained with perfect diastereoselectivity to give trans-isomer in… read more here.
Keywords: tetrahydro pyrrolo; pyrrolo imidazol; imidazol ones; cyclization reaction ... See more keywords
Silver-catalyzed decarboxylative cyclization for the synthesis of substituted pyrazoles from 1,2-diaza-1,3-dienes and α-keto acids.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc01793h
Abstract: A silver-catalyzed decarboxylative cyclization process has been developed for the synthesis of substituted pyrazoles from the readily available 1,2-diaza-1,3-dienes and α-keto acids. Under the optimized conditions, a series of multisubstituted pyrazoles were well prepared in… read more here.
Keywords: diaza dienes; synthesis substituted; decarboxylative cyclization; substituted pyrazoles ... See more keywords