Cell-free decellularized cartilage extracellular matrix scaffolds combined with interleukin 4 promote osteochondral repair through immunomodulatory macrophages: in vitro and in vivo preclinical study.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.03.054
Abstract: Cartilage regeneration is a complex physiological process. Synovial macrophages play a critical immunomodulatory role in the acute inflammatory response surrounding joint injury. Due to the contrasting differences and heterogeneity of macrophage, the phenotype of macrophages… read more here.
Keywords: decellularized cartilage; extracellular matrix; cartilage regeneration; cartilage ... See more keywords
The characterization, cytotoxicity, macrophage response and tissue regeneration of decellularized cartilage.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.09.031
Abstract: After harvesting multiple costal cartilages, the local defect disrupts the integrity of the chest wall and may lead to obvious thoracic complications, such as local depression and asymmetry of the bilateral thoracic height. Decellularized materials… read more here.
Keywords: decellularized cartilage; tissue regeneration; characterization cytotoxicity; tissue ... See more keywords
Microspheres containing decellularized cartilage induce chondrogenesis in vitro and remain functional after incorporation within a poly(caprolactone) filament useful for fabricating a 3D scaffold.
Sign Up to like & getrecommendations! Published in 2018 at "Biofabrication"
DOI: 10.1088/1758-5090/aaa637
Abstract: In this study, articular cartilage was decellularized preserving a majority of the inherent proteins, cytokines, growth factors and sGAGs. The decellularized cartilage matrix (dCM) was then encapsulated in poly(lactic acid) microspheres (MS+dCM) via double emulsion.… read more here.
Keywords: decellularized cartilage; dcm; within poly; microspheres containing ... See more keywords