Decellularized Extracellular Matrix as a Potent Natural Biomaterial for Regenerative Medicine.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2020_504
Abstract: Decellularization technique is a favorable method used to fabricate natural and tissue-like scaffolds. This technique is important because of its remarkable ability to perfectly mimic the natural extracellular matrix (ECM). ECM-based scaffolds/hydrogels provide structural support… read more here.
Keywords: medicine; regenerative medicine; extracellular matrix; matrix potent ... See more keywords
Bioprinting of 3D Tissue Models Using Decellularized Extracellular Matrix Bioink.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7021-6_27
Abstract: Bioprinting provides an exciting opportunity to print and pattern all the components that make up a tissue-cells and extracellular matrix (ECM) material-in three dimensions (3D) to generate tissue analogues. A large number of materials have… read more here.
Keywords: bioink; extracellular matrix; tissue; bioprinting tissue ... See more keywords
Decellularized extracellular matrix bioinks and the external stimuli to enhance cardiac tissue development in vitro.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.04.026
Abstract: Engineered heart tissue (EHT) has ample potential as a model for in vitro tissue modeling or tissue regeneration. Using 3D cell printing technology, various hydrogels have been utilized as bioinks to fabricate EHT to date.… read more here.
Keywords: cardiac tissue; extracellular matrix; matrix; tissue ... See more keywords
Injectable photo-crosslinking cartilage decellularized extracellular matrix for cartilage tissue regeneration
Sign Up to like & getrecommendations! Published in 2020 at "Materials Letters"
DOI: 10.1016/j.matlet.2020.127609
Abstract: Abstract Cartilage decellularized extracellular matrix (CDEM) is a promising biomaterial for preparing tissue engineering scaffolds, and CDEM-based hydrogels constitute an ideal choice for repairing cartilage damage. In this study, CDEM powders and photo-responsive hyaluronic acid… read more here.
Keywords: cdem pha; extracellular matrix; tissue; cartilage decellularized ... See more keywords
Manufacturing Considerations for Producing and Assessing Decellularized Extracellular Matrix Hydrogels.
Sign Up to like & getrecommendations! Published in 2019 at "Methods"
DOI: 10.1016/j.ymeth.2019.09.015
Abstract: Although several decellularized extracellular matrix (ECM) sheets or patches have been commercialized for use in the clinic, only one injectable decellularized ECM hydrogel, a decellularized myocardial matrix, has reached clinical trials. Consequently, very little information… read more here.
Keywords: manufacturing considerations; considerations producing; extracellular matrix; matrix ... See more keywords
Development of Enzymatic-Resistant and Compliant Decellularized Extracellular Matrixes via Aliphatic Chain Modification for Bladder Tissue Engineering.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c06865
Abstract: Here, we report the design and development of highly stretchable, compliant, and enzymatic-resistant transiently cross-linked decellularized extracellular matrixes (dECMs) (e.g., porcine small intestine submucosa/dSIS, urinary bladder matrix/dUBM, bovine pericardium/dBP, bovine dermis/dBD, and human dermis/dHD). Specifically,… read more here.
Keywords: modification; bladder; decellularized extracellular; extracellular matrixes ... See more keywords
Decellularized extracellular matrix as scaffold for cancer organoid cultures of colorectal peritoneal metastases
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjac064
Abstract: ABSTRACT Peritoneal metastases (PM) from colorectal cancer (CRC) are associated with poor survival. The extracellular matrix (ECM) plays a fundamental role in modulating the homing of CRC metastases to the peritoneum. The mechanisms underlying the… read more here.
Keywords: extracellular matrix; decellularized extracellular; peritoneal metastases; matrix scaffold ... See more keywords
Combinational Treatment Involving Decellularized Extracellular Matrix Hydrogels With Mesenchymal Stem Cells Increased the Efficacy of Cell Therapy in Pancreatitis
Sign Up to like & getrecommendations! Published in 2023 at "Cell Transplantation"
DOI: 10.1177/09636897231170437
Abstract: Cell transplantation using mesenchymal stem cells (MSCs) has emerged as a promising approach to repairing and regenerating injured or impaired organs. However, the survival and retention of MSCs following transplantation remain a challenge. Therefore, we… read more here.
Keywords: cell; extracellular matrix; decellularized extracellular; mesenchymal stem ... See more keywords
Synergistically Promoting Bone Regeneration by Icariin-Incorporated Porous Microcarriers and Decellularized Extracellular Matrix Derived From Bone Marrow Mesenchymal Stem Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.824025
Abstract: Multifunctionality has becoming essential for bone tissue engineering materials, such as drug release. In this study, icariin (ICA)-incorporated poly(glycolide-co-caprolactone) (PGCL) porous microcarriers were fabricated and then coated with decellularized extracellular matrix (dECM) which was derived… read more here.
Keywords: extracellular matrix; decellularized extracellular; bone marrow; bone ... See more keywords
Macromolecular crowding and decellularization method increase the growth factor binding potential of cell-secreted extracellular matrices
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1091157
Abstract: Recombinant growth factors are used in tissue engineering to stimulate cell proliferation, migration, and differentiation. Conventional methods of growth factor delivery for therapeutic applications employ large amounts of these bioactive cues. Effective, localized growth factor… read more here.
Keywords: extracellular matrix; decellularized extracellular; macromolecular crowding; growth ... See more keywords
Decellularized Extracellular Matrix-Based Bioinks for Tendon Regeneration in Three-Dimensional Bioprinting
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232112930
Abstract: In the last few years, attempts to improve the regeneration of damaged tendons have been rising due to the growing demand. However, current treatments to restore the original performance of the tissue focus on the… read more here.
Keywords: based bioinks; regeneration; extracellular matrix; tendon regeneration ... See more keywords