Decellularized Liver Scaffold for Liver Regeneration.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/7651_2017_53
Abstract: After being initially hailed as the ultimate solution to end-stage organ failure, such as end-stage liver disease (ESLD), engineering of vascularized tissues has stalled because of the need for a well-structured circulatory system that can… read more here.
Keywords: medicine; seed; liver regeneration; liver scaffold ... See more keywords
Decellularized liver scaffolds promote liver regeneration after partial hepatectomy
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-48948-x
Abstract: The resectable liver volume is strictly limited and this reduces the number of patients who may be treated. Recently, “tissue/organ decellularization”, a new approach in bioengineering, has been investigated for its ability to produce a… read more here.
Keywords: hepatectomy; liver scaffolds; regeneration; liver ... See more keywords
High level of polarized engraftment of porcine intrahepatic cholangiocyte organoids in decellularized liver scaffolds
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17510
Abstract: In Europe alone, each year 5500 people require a life‐saving liver transplantation, but 18% die before receiving one due to the shortage of donor organs. Whole organ engineering, utilizing decellularized liver scaffolds repopulated with autologous… read more here.
Keywords: cholangiocyte; intrahepatic cholangiocyte; porcine intrahepatic; liver scaffolds ... See more keywords
Indirect 3D Bioprinting of a Robust Trilobular Hepatic Construct with Decellularized Liver Matrix Hydrogel
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineering"
DOI: 10.3390/bioengineering9110603
Abstract: The liver exhibits complex geometrical morphologies of hepatic cells arranged in a hexagonal lobule with an extracellular matrix (ECM) organized in a specific pattern on a multi-scale level. Previous studies have utilized 3D bioprinting and… read more here.
Keywords: hydrogel; liver specific; trilobular hepatic; decellularized liver ... See more keywords
Decellularized Liver Matrices for Expanding the Donor Pool—An Evaluation of Existing Protocols and Future Trends
Sign Up to like & getrecommendations! Published in 2025 at "Biomolecules"
DOI: 10.3390/biom15010098
Abstract: Liver transplantation is the only curative option for end-stage liver disease and is necessary for an increasing number of patients with advanced primary or secondary liver cancer. Many patient groups can benefit from this treatment,… read more here.
Keywords: expanding donor; decellularized liver; liver matrices; decellularization ... See more keywords