Bisphenol A affects trophoblast invasion by inhibiting CXCL8 expression in decidual stromal cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2017.07.016
Abstract: Bisphenol A (BPA), an environmental endocrine-disrupting organic chemical, has been positively associated with the rate of implantation failure of in vitro fertilization. However, the underlying mechanisms remain unclear. To reveal the impact and the underlying mechanism… read more here.
Keywords: cxcl8 expression; trophoblast invasion; invasion; stromal cells ... See more keywords
Stromal cells of the endometrium and decidua: in search of a name and an identity
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DOI: 10.1093/biolre/ioac158
Abstract: Abstract Human endometrial and decidual stromal cells are the same cells in different environments (nonpregnancy and pregnancy, respectively). Although some authors consider decidual stromal cells to arise solely from the differentiation of endometrial stromal cells,… read more here.
Keywords: endometrial stromal; decidualization; endometrium decidua; decidual stromal ... See more keywords
Evolution of embryo implantation was enabled by the origin of decidual stromal cells in eutherian mammals.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular biology and evolution"
DOI: 10.1093/molbev/msaa274
Abstract: Mammalian pregnancy evolved in the therian stem lineage, that is, before the common ancestor of marsupials and eutherian (placental) mammals. Ancestral therian pregnancy likely involved a brief phase of attachment between the fetal and maternal… read more here.
Keywords: pregnancy; embryo implantation; stromal cells; eutherian mammals ... See more keywords
Decidual stromal cell‐derived PGE2 regulates macrophage responses to microbial threat
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DOI: 10.1111/aji.13032
Abstract: Bacterial chorioamnionitis causes adverse pregnancy outcomes, yet host‐microbial interactions are not well characterized within gestational membranes. The decidua, the outermost region of the membranes, is a potential point of entry for bacteria ascending from the… read more here.
Keywords: responses microbial; stromal cell; cell derived; derived pge2 ... See more keywords
Decidual stromal cells maintain decidual macrophage homeostasis by secreting IL‐24 in early pregnancy
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DOI: 10.1111/aji.13261
Abstract: The state of self‐renewal and self‐maintain of decidual macrophages would be important for immune homeostasis at the maternal‐fetal interface. The roles of interleukin (IL)‐24 derived from decidual stromal cells (DSCs) on decidual macrophages have not… read more here.
Keywords: homeostasis; stromal cells; maintain decidual; cells maintain ... See more keywords
Decidual CD8+T cells exhibit both residency and tolerance signatures modulated by decidual stromal cells
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DOI: 10.1186/s12967-020-02371-3
Abstract: During early pregnancy, tolerance of the semi-allogeneic fetus necessitates comprehensive modifications of the maternal immune system. How decidual CD8+T (CD8+dT) cells balance maternal tolerance of the fetus with defense from invading pathogens remains undefined. We… read more here.
Keywords: cd8; tolerance; residency; cd8 cells ... See more keywords
Decidual Small Extracellular Vesicles induce Trophoblast Invasion by upregulating N-cadherin.
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DOI: 10.1530/rep-18-0616
Abstract: Small extracellular vesicles (sEVs) are important mediators of cell-to-cell communication involved in successful establishment of a pregnancy. Human decidual stromal cells play a key role in regulating trophoblast invasion. Nevertheless, the regulatory functions of decidual… read more here.
Keywords: invasion; hdsc sevs; trophoblast cells; stromal cells ... See more keywords
Cell type markers indicate distinct contributions of decidual stromal cells and natural killer cells in preeclampsia.
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DOI: 10.1530/rep-22-0079
Abstract: Preeclampsia is a devastating pregnancy disorder and a major cause of maternal and perinatal mortality. By combining previous transcriptomic results on preeclampsia with single-cell sequencing (scRNA-seq) data, we here predict distinct and partly unanticipated contributions… read more here.
Keywords: cell; natural killer; killer cells; contributions decidual ... See more keywords