Deciphering deamidation and isomerization in therapeutic proteins: Effect of neighboring residue
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DOI: 10.1080/19420862.2022.2143006
Abstract: ABSTRACT Deamidation of asparagine (Asn) and isomerization of aspartic acid (Asp) residues are among the most commonly observed spontaneous post-translational modifications (PTMs) in proteins. Understanding and predicting a protein sequence’s propensity for such PTMs can… read more here.
Keywords: deamidation; deamidation isomerization; therapeutic proteins; isomerization ... See more keywords