Deciphering the Molecular Effects of Mutations on ATRX Cause ATRX Syndrome: A Molecular Dynamics Study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25984
Abstract: α‐thalassemia mental retardation X‐linked (ATRX) syndrome is caused by the dysfunction of ATRFfigX protein. The present study explored the structural consequences influenced by two observed mutations V194I and C220R on ADD domain of ATRX protein… read more here.
Keywords: deciphering molecular; molecular dynamics; atrx syndrome; add domain ... See more keywords
Deciphering the molecular events during arsenic induced transcription signal cascade activation in cellular milieu
Sign Up to like & getrecommendations! Published in 2017 at "BioMetals"
DOI: 10.1007/s10534-017-0065-3
Abstract: Anthropogenic sources of arsenic poses and creates unintentional toxico-pathological concerns to humans in many parts of the world. The understanding of toxicity of this metalloid, which shares properties of both metal and non-metal is principally… read more here.
Keywords: deciphering molecular; transcription; events arsenic; molecular events ... See more keywords
Deciphering molecular properties and docking studies of hepatitis C and non‐hepatitis C antiviral inhibitors ‐ A computational approach
Sign Up to like & getrecommendations! Published in 2017 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.02.014
Abstract: Background: Hepatitis C is an infectious liver disease with high mortality rate which is caused by Hepatitis C virus. Several treatment methods have been applied to combat this deadly virus including interferons, vaccine and direct… read more here.
Keywords: properties docking; deciphering molecular; antiviral inhibitors; inhibitor ... See more keywords
Abstract 1229: Deciphering molecular mechanisms of metastasis in renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1229
Abstract: Across human cancer, tumors that are high grade, poorly differentiated, and have undergone epithelial-to-mesenchymal transition (EMT) carry a worse prognosis with a high likelihood of metastasizing to distant organs. Despite significant research efforts, metastatic cancers… read more here.
Keywords: cell; cell carcinoma; renal cell; deciphering molecular ... See more keywords