Long-term effect of α1-antitrypsin augmentation therapy on the decline of FEV1 in deficient patients: an analysis of the AIR database
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DOI: 10.1183/23120541.00194-2021
Abstract: Background Patients with ZZ (Glu342Lys) α-1-antitrypsin deficiency (ZZ-AATD) who received augmentation therapy with α-1-antitrypsin (AAT) in randomised controlled trials over 2–3 years failed to show a significant reduction of the annual decline of forced expiratory volume… read more here.
Keywords: decline; augmentation therapy; decline fev1; augmentation ... See more keywords
Obstructive sleep apnoea accelerates FEV1 decline in asthmatic patients
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DOI: 10.1186/s12890-017-0398-2
Abstract: BackgroundAlthough the prevalence of both obstructive sleep apnoea (OSA) and asthma are both increasing, little is known about the impact of OSA on the natural history of lung function in asthmatic patients.MethodsA total of 466… read more here.
Keywords: apnoea; decline fev1; decline; obstructive sleep ... See more keywords