Inhibition of phosphodiesterase 4 by FCPR16 protects SH-SY5Y cells against MPP+-induced decline of mitochondrial membrane potential and oxidative stress
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DOI: 10.1016/j.redox.2018.02.008
Abstract: Phosphodiesterase 4 (PDE4) is a promising target for the treatment of Parkinson's disease (PD). However, the underlying mechanism has not yet been well elucidated. Additionally, most of current PDE4 inhibitors produce severe nausea and vomiting… read more here.
Keywords: mpp induced; fcpr16; mitochondrial membrane; membrane potential ... See more keywords