Neuronal autophagy declines substantially with age and is rescued by overexpression of WIPI2
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DOI: 10.1080/15548627.2019.1695401
Abstract: ABSTRACT Macroautophagy/autophagy is implicated in age-dependent neurodegenerative diseases, including amyotrophic lateral sclerosis and Parkinson, Huntington and Alzheimer diseases, suggesting that an age-related decline in neuronal autophagy may contribute to the onset of neurodegeneration. We identified… read more here.
Keywords: autophagy declines; age; declines substantially; autophagy ... See more keywords