Chondroitin sulfate content and decorin expression in glioblastoma are associated with proliferative activity of glioma cells and disease prognosis
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DOI: 10.1007/s00441-019-03127-2
Abstract: Chondroitin sulfate proteoglycans (CSPGs) are important components of brain extracellular matrix (ECM), although their contribution in gliomagenesis remains underinvestigated. Here, both chondroitin sulfate (CS) content/distribution and expression of a number of CSPG core proteins were… read more here.
Keywords: gbm; content; chondroitin sulfate; expression ... See more keywords
Decorin Expression Is Associated With Diffusion MR Phenotypes in Glioblastoma
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DOI: 10.1093/neuros/nyz310_809
Abstract: Significant evidence from multiple phase II trials have suggested diffusion-weighted imaging estimates of apparent diffusion coefficient (ADC) are a predictive imaging biomarker for survival benefit for recurrent glioblastoma when treated with anti-VEGF therapies, including bevacizumab,… read more here.
Keywords: expression; diffusion imaging; diffusion; decorin expression ... See more keywords