Articles with "decreased systemic" as a keyword



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Evodiamine decreased the systemic exposure of pravastatin in non-alcoholic steatohepatitis rats due to the up-regulation of hepatic OATPs

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Published in 2022 at "Pharmaceutical Biology"

DOI: 10.1080/13880209.2022.2036767

Abstract: Abstract Context Patients with non-alcoholic steatohepatitis (NASH) may have a simultaneous intake of pravastatin and evodiamine-containing herbs. Objective The effect of evodiamine on the pharmacokinetics of pravastatin and its potential mechanisms were investigated in NASH… read more here.

Keywords: non alcoholic; evodiamine decreased; evodiamine; pravastatin ... See more keywords