Decreased vitamin C uptake mediated by SLC2A3 promotes leukaemia progression and impedes TET2 restoration
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DOI: 10.1038/s41416-020-0788-8
Abstract: Vitamin C suppresses leukaemogenesis by modulating Tet methylcytosine dioxygenase (TET) activity. However, its beneficial effect in the treatment of patients with acute myeloid leukaemia (AML) remains controversial. In this study, we aimed to identify a… read more here.
Keywords: aml; decreased vitamin; slc2a3 expression; cell ... See more keywords