Aspergillus fumigatus Induces the Release of IL-8 and MCP-1 by Activating Nuclear Transcription Through Dectin-1 and CR3 Receptors in Alveolar Epithelial Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Current microbiology"
DOI: 10.1007/s00284-021-02534-5
Abstract: Invasive pulmonary aspergillosis induced by the pathogenic fungus Aspergillus fumigatus is one of the common fatal complications in immunocompromised patients. Lung epithelial cells play an important role in host immune defense against A. fumigatus. However,… read more here.
Keywords: aspergillus fumigatus; epithelial cells; cr3 receptors; dectin ... See more keywords
The Expression of Dectin-1, Irak1 and Rip2 During the Host Response to Aspergillus fumigatus
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DOI: 10.1007/s11046-017-0210-0
Abstract: BackgroundC-type lectin receptors (CLRs), Toll-like receptors (TLRs), and Nod-like receptors (NLRs) have the ability to recognize Aspergillus fumigatus (A. fumigates) and induce innate immune response. Dectin-1 is a well-described CLR, while interleukin-1 receptor-associated kinase 1… read more here.
Keywords: response; expression; dectin; dectin irak1 ... See more keywords
Dectin-1 rs3901533 and rs7309123 Polymorphisms Increase Susceptibility to Pulmonary Invasive Fungal Disease in Patients with Acute Myeloid Leukemia from a Chinese Han Population
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DOI: 10.1007/s11596-019-2122-3
Abstract: This study aimed to assess whether genetic variants of dendritic cell-associated C-type lectine-1 (Dectin-1), Toll-like receptor 2 (TLR2), Toll-like receptor 4 (TLR4), and myeloid differentiation primary response 88 (MyD88) influence the susceptibility to pulmonary invasive… read more here.
Keywords: rs7309123; ifd; rs3901533; dectin ... See more keywords
Water-soluble polysaccharides from Pleurotus eryngii fruiting bodies, their activity and affinity for Toll-like receptor 2 and dectin-1.
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DOI: 10.1016/j.carbpol.2021.117991
Abstract: The mushroom cell wall contains polysaccharides that can activate cells of the innate immune system through receptors such as Toll-like receptors (TLR) and dectin-1. In the present study, Pleurotus eryngii polysaccharide fractions containing a 3-O… read more here.
Keywords: toll like; receptor dectin; pleurotus eryngii; water soluble ... See more keywords
Dectin-1 Activation Exacerbates Obesity and Insulin Resistance in the Absence of MyD88.
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DOI: 10.1016/j.celrep.2017.05.059
Abstract: The underlying mechanism by which MyD88 regulates the development of obesity, metainflammation, and insulin resistance (IR) remains unknown. Global deletion of MyD88 in high-fat diet (HFD)-fed mice resulted in increased weight gain, impaired glucose homeostasis,… read more here.
Keywords: cd11c macrophages; insulin resistance; dectin; absence myd88 ... See more keywords
Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response.
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DOI: 10.1016/j.celrep.2020.03.018
Abstract: Colonic macrophages are considered to be major effectors of inflammatory bowel diseases (IBDs) and the control of gut inflammation through C-type lectin receptors is an emerging concept. We show that during colitis, the loss of… read more here.
Keywords: divergent roles; inflammation; type lectin; dectin ... See more keywords
Oat β-glucan ameliorates epidermal barrier disruption by upregulating the expression of CaSR through dectin-1-mediated ERK and p38 signaling pathways.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.07.002
Abstract: The integrity of the epidermal barrier and the maintenance of barrier homeostasis depend on the dynamic balance between the proliferation and differentiation of keratinocytes. Calcium (Ca2+) plays a crucial role in maintaining a balance of… read more here.
Keywords: barrier; oat glucan; erk p38; epidermal barrier ... See more keywords
Dectin-1 on macrophages modulates the immune response to Fasciola hepatica products through the ERK signaling pathway.
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DOI: 10.1016/j.imbio.2018.08.004
Abstract: Fasciolosis is a zoonotic disease of increasing importance due to its worldwide distribution and elevated economic losses. Previously, we demonstrated that Fasciola hepatica excretory-secretory products (FhESP) induce immunomodulatory effects on peritoneal macrophages in a Dectin-1… read more here.
Keywords: fasciola hepatica; peritoneal macrophages; hepatica products; hepatica ... See more keywords
The role of dectin-1 in health and disease.
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DOI: 10.1016/j.imbio.2021.152071
Abstract: Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). This CLR identifies ligands independently of Ca2+ and… read more here.
Keywords: health disease; dectin health; role; dectin ... See more keywords
Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M.
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DOI: 10.1016/j.immuni.2021.01.004
Abstract: Pathologic roles of innate immunity in neurologic disorders are well described, but their beneficial aspects are less understood. Dectin-1, a C-type lectin receptor (CLR), is largely known to induce inflammation. Here, we report that Dectin-1… read more here.
Keywords: autoimmune neuroinflammation; myeloid cell; card9 independent; cell astrocyte ... See more keywords
The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception
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DOI: 10.1016/j.isci.2018.08.007
Abstract: Summary Candida albicans infection can cause skin, vulvar, or oral pain. Despite the obvious algesic activity of C. albicans, the molecular mechanisms of fungal nociception remain largely unknown. Here we show that the C. albicans-specific… read more here.
Keywords: transporter vnut; nociception; atp transporter; vnut ... See more keywords