Dectin‐1 signaling in neutrophils up‐regulates PD‐L1 and triggers ROS‐mediated suppression of CD4+ T cells
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DOI: 10.1002/jlb.3a0322-152rr
Abstract: Dectin‐1 is known to drive proinflammatory cytokine production by macrophages and dendritic cells which promotes Th17 CD4+ T cell responses in the setting of fungal infection. However, the role of Dectin‐1 signaling in neutrophils and… read more here.
Keywords: dectin signaling; cd4 cells; cd4; signaling neutrophils ... See more keywords
Paeonol ameliorates murine alcohol liver disease via mycobiota‐mediated Dectin‐1/IL‐1β signaling pathway
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DOI: 10.1002/jlb.3ma0120-325rr
Abstract: Alcoholic liver disease (ALD) is caused by long‐term consumption of alcohol and has become an important social and medical problem. Intestinal fungal flora (mycobiota) play an important role in ALD, so we used the mycobiota… read more here.
Keywords: ald; mediated dectin; signaling pathway; dectin signaling ... See more keywords
Dectin-1 Signaling Update: New Perspectives for Trained Immunity
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DOI: 10.3389/fimmu.2022.812148
Abstract: The C-type lectin receptor Dectin-1 was originally described as the β-glucan receptor expressed in myeloid cells, with crucial functions in antifungal responses. However, over time, different ligands both of microbial-derived and endogenous origin have been… read more here.
Keywords: dectin signaling; trained immunity; signaling update; update new ... See more keywords