Decursin and decursinol angelate improve wound healing by upregulating transcription of genes encoding extracellular matrix remodeling proteins, inflammatory cytokines, and growth factors in human keratinocytes.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.04.031
Abstract: The coumarins decursin and decursinol angelate, which are found in Angelica gigas Nakai, have a variety of biological functions. Here, we show that treatment with these compounds improves wound healing by HaCaT human keratinocytes. Wound… read more here.
Keywords: wound healing; growth; decursin decursinol; decursinol angelate ... See more keywords
Decursin and decursinol angelate-rich Angelica gigas Nakai extract suppresses de novo lipogenesis and alleviates nonalcoholic fatty liver disease and dyslipidemia in mice fed a high fat diet
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DOI: 10.1016/j.jff.2017.02.008
Abstract: Abstract Metabolically beneficial effects of decursin and decursinol angelate have been reported. However, it is unclear whether Angelica gigas Nakai extract (AGNE), which is rich in decursin and decursinol angelate, can alleviate high-fat diet (HFD)-mediated… read more here.
Keywords: novo lipogenesis; decursinol angelate; decursin decursinol;
Decursinol Angelate Mitigates Sepsis Induced by Methicillin-Resistant Staphylococcus aureus Infection by Modulating the Inflammatory Responses of Macrophages
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DOI: 10.3390/ijms222010950
Abstract: The herbal plant Angelica gigas (A. gigas) has been used in traditional medicine in East Asian countries, and its chemical components are reported to have many pharmacological effects. In this study, we showed that a… read more here.
Keywords: methicillin resistant; decursinol angelate; staphylococcus aureus; resistant staphylococcus ... See more keywords