Three-dimensional spheroids of dedifferentiated fat cells enhance bone regeneration
Sign Up to like & getrecommendations! Published in 2021 at "Regenerative Therapy"
DOI: 10.1016/j.reth.2021.10.004
Abstract: Introduction Mesenchymal stromal/stem cells (MSCs) are multipotent, self-renewing cells that are extensively used in tissue engineering. Dedifferentiated fat (DFAT) cells are derived from adipose tissues and are similar to MSCs. Three-dimensional (3D) spheroid cultures comprising… read more here.
Keywords: bone; dfat cells; three dimensional; cells spheroids ... See more keywords
The neovascularization effect of dedifferentiated fat cells
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-66135-1
Abstract: Mature adipocyte-derived dedifferentiated fat (DFAT) cells can be prepared efficiently and with minimal invasiveness to the donor. They can be utilized as a source of transplanted cells during therapy. Although the transplantation of DFAT cells… read more here.
Keywords: dfat; neovascularization effect; fat cells; effect dedifferentiated ... See more keywords
Transplantation of mature adipocyte-derived dedifferentiated fat cells into three-wall defects in the rat periodontium induces tissue regeneration.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of oral science"
DOI: 10.2334/josnusd.16-0878
Abstract: The transplantation of dedifferentiated fat (DFAT) cells in combination with poly(d,l-lactic-co-glycolic acid) (PLGA) scaffolds has previously been proven as an effective approach in promoting periodontal tissue regeneration in a rat fenestration defect model. The aim… read more here.
Keywords: three wall; tissue regeneration; regeneration; dfat ... See more keywords
Transplantation of Mature Adipocyte-Derived Dedifferentiated Fat Cells Facilitates Periodontal Tissue Regeneration of Class II Furcation Defects in Miniature Pigs
Sign Up to like & getrecommendations! Published in 2022 at "Materials"
DOI: 10.3390/ma15041311
Abstract: Adipose tissue is composed mostly of adipocytes that are in contact with capillaries. By using a ceiling culture method based on buoyancy, lipid-free fibroblast-like cells, also known as dedifferentiated fat (DFAT) cells, can be separated… read more here.
Keywords: dfat cells; furcation defects; tissue; dedifferentiated fat ... See more keywords
Senescence-associated secretory phenotypes in rat-derived dedifferentiated fat cells with replicative senescence.
Sign Up to like & getrecommendations! Published in 2023 at "Dental materials journal"
DOI: 10.4012/dmj.2022-242
Abstract: Senescence-associated secretory phenotype (SASPs) secreted from senescent cells often cause the deleterious damages to the surrounding tissues. Although dedifferentiated fat (DFAT) cells prepared are considered a promising cell source for regenerative therapies, SASPs from DFAT… read more here.
Keywords: dfat cells; dedifferentiated fat; associated secretory; senescence ... See more keywords