Activity of Cabazitaxel in Metastatic or Inoperable Locally Advanced Dedifferentiated Liposarcoma: A Phase 2 Study of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG).
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.3218
Abstract: Importance Treatment options for patients with unresectable and/or metastatic dedifferentiated liposarcoma (DDLPS) are limited. New drugs are required. Objective To assess whether cabazitaxel demonstrated sufficient antitumor activity in patients with metastatic or inoperable locally advanced… read more here.
Keywords: locally advanced; metastatic inoperable; dedifferentiated liposarcoma; activity ... See more keywords
First‐line chemotherapy in advanced intra‐abdominal well‐differentiated/dedifferentiated liposarcoma: An EORTC Soft Tissue and Bone Sarcoma Group retrospective analysis
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34264
Abstract: No prospective trial with anthracycline‐based chemotherapy has individually assessed response in a well‐differentiated (WD)/dedifferentiated (DD) liposarcoma patient cohort. We conducted a retrospective analysis of first‐line chemotherapy in liposarcoma of intra‐abdominal origin (IA‐LPS) in patients who… read more here.
Keywords: differentiated dedifferentiated; dedifferentiated liposarcoma; first line; chemotherapy ... See more keywords
An oncologic emergency case of massive dedifferentiated liposarcoma of the small bowel mesentery
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Journal of Gastroenterology"
DOI: 10.1007/s12328-021-01350-5
Abstract: We report the case of a 71-year-old man who complained of abdominal distension, pedal edema, respiratory discomfort, and weight gain. Computed tomography revealed a giant, poorly enhancing tumor occupying the entire abdomen, with abdominal ascites.… read more here.
Keywords: small bowel; case; emergency; dedifferentiated liposarcoma ... See more keywords
Anti-tumor effects of anti-PD-1 antibody, pembrolizumab, in humanized NSG PDX mice xenografted with dedifferentiated liposarcoma.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.02.042
Abstract: The efficacy of an immune checkpoint blockade has been demonstrated against various types of cancer, but its suitability has not been fully proven for therapies specifically targeting sarcoma. We conducted a pan-cancer tumor data analysis… read more here.
Keywords: anti antibody; mice xenografted; xenografted dedifferentiated; tumor effects ... See more keywords
Dedifferentiated liposarcoma of the spermatic cord: Case report and review of literature
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Surgery Case Reports"
DOI: 10.1016/j.ijscr.2020.06.051
Abstract: Highlights • Liposarcomas typically presents as bulky heterogeneous solid lesions that are larger/firmer than simple “cord lipoma.” Tumors range from 3 to 30 cm in diameter.• Current controversy in management of liposarcomas pertains to the use… read more here.
Keywords: liposarcoma spermatic; cord case; cord; case ... See more keywords
Polypoid fibroadipose tumors of the esophagus: ‘giant fibrovascular polyp’ or liposarcoma? A clinicopathological and molecular cytogenetic study of 13 cases
Sign Up to like & getrecommendations! Published in 2018 at "Modern Pathology"
DOI: 10.1038/modpathol.2017.140
Abstract: Giant fibrovascular polyp of the esophagus is a descriptive diagnostic term intended to encompass rare, large, polypoid esophageal masses composed of fibroadipose tissue. Despite sometimes dramatic clinical presentations, they have historically been considered to represent… read more here.
Keywords: liposarcoma; fibrovascular polyp; well differentiated; dedifferentiated liposarcoma ... See more keywords
Mediastinal dedifferentiated liposarcoma
Sign Up to like & getrecommendations! Published in 2017 at "Acta Cardiologica"
DOI: 10.1080/00015385.2017.1335460
Abstract: In a healthy 71-year-old Caucasian man, incidentally chest X-ray showed a huge mediastinal mass (figure 1A). A chest CT-scan confirmed a bulky mass with inhomogeneous structure and colliquation are... read more here.
Keywords: mediastinal dedifferentiated; dedifferentiated liposarcoma;
Retroperitoneal Dedifferentiated Liposarcoma.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqab051
Abstract: OBJECTIVES We aimed to test the hypothesis that in retroperitoneal dedifferentiated liposarcoma (DDLS) the presence of the dedifferentiated (DD) component at the resection margin is associated with adverse outcome. METHODS We retrospectively searched the archive… read more here.
Keywords: presence; retroperitoneal; dedifferentiated liposarcoma; retroperitoneal dedifferentiated ... See more keywords
Long-term disease control by trabectedin in a patient with dedifferentiated liposarcoma
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000018689
Abstract: Abstract Rationale: Trabectedin is an antitumor drug considered to be effective for liposarcoma, leiomyosarcoma, and translocation-related sarcoma. Concerning liposarcoma subtypes, evidence of the efficacy of trabectedin for dedifferentiated liposarcoma (DDLPS) is poor, whereas it is… read more here.
Keywords: patient; term disease; term; dedifferentiated liposarcoma ... See more keywords
Rare paratesticular localization of dedifferentiated liposarcoma: Case report and review of the literature
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033265
Abstract: Rationale: Dedifferentiated liposarcoma is defined as a malignant tumor that changes its shape from a well-differentiated liposarcoma to a non-liposarcomatous form. Most paratesticular liposarcomas manifest as an inguinal, painless, slow-growing mass. The standard treatment is… read more here.
Keywords: paratesticular localization; rare paratesticular; dedifferentiated liposarcoma; localization dedifferentiated ... See more keywords
18F-FDG PET/CT Imaging of G-CSF-Producing Dedifferentiated Liposarcoma.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000003783
Abstract: ABSTRACT Granulocyte colony-stimulating factor (G-CSF)-producing tumors are malignant tumors associated with a poor prognosis, and G-CSF-producing liposarcoma is particularly rare. We report a case of G-CSF-producing dedifferentiated liposarcoma. 18F-FDG PET/CT showed abnormal 18F-FDG uptake throughout… read more here.
Keywords: fdg pet; 18f fdg; dedifferentiated liposarcoma; csf producing ... See more keywords