Islet cell dedifferentiation is a pathologic mechanism of long-standing progression of type 2 diabetes.
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DOI: 10.1172/jci.insight.143791
Abstract: Dedifferentiation has been implicated in β cell dysfunction and loss in rodent diabetes. However, the pathophysiological significance in humans remains unclear. To elucidate this, we analyzed surgically resected pancreatic tissues of 26 Japanese subjects with… read more here.
Keywords: cell dedifferentiation; dedifferentiation pathologic; progression; cell ... See more keywords