Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-04668-w
Abstract: Lipoprotein(a), Lp(a), is a modified low-density lipoprotein particle that contains apolipoprotein(a), encoded by LPA, and is a highly heritable, causal risk factor for cardiovascular diseases that varies in concentrations across ancestries. Here, we use deep-coverage… read more here.
Keywords: coverage whole; whole genome; deep coverage; individuals european ... See more keywords
Deep-Coverage MPS Analysis of Heteroplasmic Variants within the mtGenome Allows for Frequent Differentiation of Maternal Relatives
Sign Up to like & getrecommendations! Published in 2018 at "Genes"
DOI: 10.3390/genes9030124
Abstract: Distinguishing between maternal relatives through mitochondrial (mt) DNA sequence analysis has been a longstanding desire of the forensic community. Using a deep-coverage, massively parallel sequencing (DCMPS) approach, we studied the pattern of mtDNA heteroplasmy across… read more here.
Keywords: analysis; maternal relatives; deep coverage; differentiating heteroplasmy ... See more keywords