Deep enzymology studies on DNA methyltransferases reveal novel connections between flanking sequences and enzyme activity.
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DOI: 10.1016/j.jmb.2021.167186
Abstract: DNA interacting enzymes recognize their target sequences embedded in variable flanking sequence context. The influence of flanking sequences on enzymatic activities of DNA methyltransferases (DNMTs) can be systematically studied with "deep enzymology" approaches using pools… read more here.
Keywords: flanking sequences; dna; deep enzymology; enzymology ... See more keywords