Effect of the enantiomeric structure of hydrophobic polymers on the encapsulation properties of a second near infrared (NIR-II) fluorescent dye for in vivo deep imaging
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DOI: 10.1039/d1ra08330a
Abstract: Over-thousand-nanometer (OTN) near-infrared (NIR) fluorophores are useful for biological deep imaging because of the reduced absorption and scattering of OTN-NIR light in biological tissues. IR-1061, an OTN-NIR fluorescent dye, has a hydrophobic and cationic backbone… read more here.
Keywords: deep imaging; nir fluorescent; hydrophobic; dye ... See more keywords
Deep imaging in the brainstem reveals functional heterogeneity in V2a neurons controlling locomotion
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DOI: 10.1126/sciadv.abc6309
Abstract: Calcium imaging of genetically defined neurons in the ventral brainstem during locomotion reveals unexpected functional diversity. V2a neurons are a genetically defined cell class that forms a major excitatory descending pathway from the brainstem reticular… read more here.
Keywords: locomotion; v2a neurons; imaging brainstem; deep imaging ... See more keywords
Deep Imaging to Dissect Microvascular Contributions to White Matter Degeneration in Rodent Models of Dementia
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DOI: 10.1161/strokeaha.122.037156
Abstract: The increasing socio-economic burden of Alzheimer disease (AD) and AD-related dementias has created a pressing need to define targets for therapeutic intervention. Deficits in cerebral blood flow and neurovascular function have emerged as early contributors… read more here.
Keywords: white matter; rodent; deep imaging; related dementias ... See more keywords