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   Articles with "deep immune" as a keyword



Deep immune profiling of patients treated with lenalidomide and dexamethasone with or without daratumumab

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recommendations! Published in 2020 at "Leukemia"

DOI: 10.1038/s41375-020-0855-4

Abstract: CD38-targeted antibody, daratumumab, is approved for the treatment of multiple myeloma (MM). Phase 1/2 studies GEN501/SIRIUS revealed a novel immunomodulatory mechanism of action (MOA) of daratumumab that enhanced the immune response, reducing natural killer (NK)… read more here.

Keywords: profiling patients; deep immune; dexamethasone; immune profiling ... See more keywords

Deep immune cell profiling in blood and bone marrow of early stage monoclonal gammopathy: an iStopMM and ECRIN-M3 collaborative study

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recommendations! Published in 2025 at "Blood Cancer Journal"

DOI: 10.1038/s41408-025-01255-3

Abstract: Dear Editor, Increasing evidences support a key role of the immune system in the development and progression of monoclonal gammopathies (MG), i.e., from premalignant stages — e.g., MG of undetermined signi fi cance (MGUS), smoldering… read more here.

Keywords: profiling blood; cell profiling; deep immune; immune cell ... See more keywords

Deep immune profiling delineates hallmarks of disease heterogeneity in extrapulmonary tuberculosis

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recommendations! Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-65561-x

Abstract: Our understanding of the immune response in tuberculosis (TB) remains incomplete. This applies in particular to extrapulmonary TB (EPTB), a highly heterogeneous disease affecting up to 30% of patients in certain regions. Based on data-driven… read more here.

Keywords: extrapulmonary tuberculosis; tuberculosis; profiling delineates; deep immune ... See more keywords

Deep immune profiling uncovers novel associations with clinical phenotypes of multisystem inflammatory syndrome in children (MIS-C)

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recommendations! Published in 2022 at "Annals of the Rheumatic Diseases"

DOI: 10.1136/ard-2022-223269

Abstract: Multisystem inflammatory syndrome in children (MISC) is a systemic inflammatory condition seen in children following SARSCoV2 infection or exposure. Symptoms are highly variable and include fever, diarrhoea, cardiogenic shock, respiratory compromise and Kawasaki disease (KD)like… read more here.

Keywords: deep immune; immune profiling; inflammatory syndrome; syndrome children ... See more keywords