Deep immune profiling of patients treated with lenalidomide and dexamethasone with or without daratumumab
Sign Up to like & getrecommendations! Published in 2020 at "Leukemia"
DOI: 10.1038/s41375-020-0855-4
Abstract: CD38-targeted antibody, daratumumab, is approved for the treatment of multiple myeloma (MM). Phase 1/2 studies GEN501/SIRIUS revealed a novel immunomodulatory mechanism of action (MOA) of daratumumab that enhanced the immune response, reducing natural killer (NK)… read more here.
Keywords: profiling patients; deep immune; dexamethasone; immune profiling ... See more keywords
Deep immune profiling uncovers novel associations with clinical phenotypes of multisystem inflammatory syndrome in children (MIS-C)
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/ard-2022-223269
Abstract: Multisystem inflammatory syndrome in children (MISC) is a systemic inflammatory condition seen in children following SARSCoV2 infection or exposure. Symptoms are highly variable and include fever, diarrhoea, cardiogenic shock, respiratory compromise and Kawasaki disease (KD)like… read more here.
Keywords: deep immune; immune profiling; inflammatory syndrome; syndrome children ... See more keywords