Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression
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DOI: 10.1016/j.neuron.2019.12.015
Abstract: Alzheimer's disease (AD) displays a long asymptomatic stage before dementia. We characterize AD stage-associated molecular networks by profiling 14,513 proteins and 34,173 phosphosites in the human brain with mass spectrometry, highlighting 173 protein changes in… read more here.
Keywords: deep multilayer; alzheimer disease; molecular networks; progression ... See more keywords