Soft X-Ray Stimulated Lanthanide@MOF Nanoprobe for Amplifying Deep Tissue Synergistic Photodynamic and Antitumor Immunotherapy.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202101174
Abstract: Combining photodynamic therapy (PDT) and immunotherapy has shown profound impact for synergistic treatment of malignant tumors. However, the shallow penetration depth of the traditional visible light activated PDT, immunosuppressive tumor microenvironment (TME), and poor immunogenicity… read more here.
Keywords: deep tissue; immunotherapy; ray; pdt ... See more keywords
Simultaneous Nanothermometry and Deep‐Tissue Imaging
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Science"
DOI: 10.1002/advs.202000370
Abstract: Abstract Bright, stable, and biocompatible fluorescent contrast agents operating in the second biological window (1000–1350 nm) are attractive for imaging of deep‐lying structures (e.g., tumors) within tissues. Ideally, these contrast agents also provide functional insights,… read more here.
Keywords: contrast agents; deep tissue; tissue imaging; simultaneous nanothermometry ... See more keywords
Low Dose Soft X‐Ray Remotely Triggered Lanthanide Nanovaccine for Deep Tissue CO Gas Release and Activation of Systemic Anti‐Tumor Immunoresponse
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Science"
DOI: 10.1002/advs.202004391
Abstract: Abstract Gas‐based therapy has emerged as a new green therapy strategy for anti‐tumor treatment. However, the therapeutic efficacy is still restricted by the deep tissue controlled release, poor lymphocytic infiltration, and inherent immunosuppressive tumor microenvironment… read more here.
Keywords: deep tissue; anti tumor; soft ray; tumor ... See more keywords
Vector‐Free Deep Tissue Targeting of DNA/RNA Therapeutics via Single Capacitive Discharge Conductivity‐Clamped Gene Electrotransfer (Adv. Sci. 3/2025)
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202570016
Abstract: DNA/RNA Therapeutics Single pulse electrotransfer of ‘naked’ DNA / mRNA via electric field focusing for deep tissue and vaccine therapeutics. In article 2406545, Jeremy L. Pinyon, Georg von Jonquieres, Gary D. Housley, and co‐workers describe… read more here.
Keywords: dna rna; deep tissue; electrotransfer; rna therapeutics ... See more keywords
Recent Advances in Near-Infrared-II Fluorescence Imaging for Deep-Tissue Molecular Analysis and Cancer Diagnosis.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202202035
Abstract: Fluorescence imaging with high sensitivity and minimal invasiveness has received tremendous attention, which can accomplish visualized monitoring and evaluation of cancer progression. Compared with the conventional first near-infrared (NIR-I) optical window (650-950 nm), fluorescence imaging in… read more here.
Keywords: deep tissue; fluorescence imaging; nir fluorescence; cancer ... See more keywords
Upconverting CeO2: Yb3+/Tm3+ hollow nanospheres for photo-thermal sterilization and deep-tissue imaging in the first biological window
Sign Up to like & getrecommendations! Published in 2019 at "Ceramics International"
DOI: 10.1016/j.ceramint.2019.07.202
Abstract: Abstract The up-conversion emissions falling within the first biological window (NIR-I, 650–1000 nm) are very important in deep tissue imaging due to their large penetration depths. Herein, the hollow-structured CeO2: Yb3+/Tm3+ nanospheres with red and near-infrared… read more here.
Keywords: tissue imaging; yb3 tm3; ceo2 yb3; deep tissue ... See more keywords
Effects of deep tissue massage on pain and comfort after cesarean: A randomized controlled trial.
Sign Up to like & getrecommendations! Published in 2021 at "Complementary therapies in clinical practice"
DOI: 10.1016/j.ctcp.2021.101320
Abstract: PURPOSE In this study, it was aimed to determine the effect of deep tissue massage (DTM) applied by midwife on pain and comfort after cesarean section. MATERIAL AND METHODS This study was designed as a… read more here.
Keywords: deep tissue; comfort cesarean; pain comfort; group ... See more keywords
Ultrasound-Activated PROTAC Prodrugs Overcome Immunosuppression to Actuate Efficient Deep-Tissue Sono-Immunotherapy in Orthotopic Pancreatic Tumor Mouse Models.
Sign Up to like & getrecommendations! Published in 2024 at "Nano letters"
DOI: 10.1021/acs.nanolett.4c02287
Abstract: The degradation of oncoproteins mediated by proteolysis-targeting chimera (PROTAC) has emerged as a potent strategy in cancer therapy. However, the clinical application of PROTACs is hampered by challenges such as poor water solubility and off-target… read more here.
Keywords: sono immunotherapy; deep tissue; mouse; orthotopic ... See more keywords
Multifunctional Self-Assembled Supernanoparticles for Deep-Tissue Bimodal Imaging and Amplified Dual-Mode Heating Treatment.
Sign Up to like & getrecommendations! Published in 2019 at "ACS nano"
DOI: 10.1021/acsnano.8b06563
Abstract: Developing multifunctional therapeutic and diagnostic (theranostic) nanoplatforms is critical for addressing challenging issues associated with cancers. Here, self-assembled supernanoparticles consisting of superparamagnetic Fe3O4 nanoparticles and photoluminescent PbS/CdS quantum dots whose emission lies within the second… read more here.
Keywords: assembled supernanoparticles; dual mode; deep tissue; self assembled ... See more keywords
Deep-tissue high-sensitivity multimodal imaging and optogenetic manipulation enabled by biliverdin reductase knockout
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-61532-4
Abstract: Performance of near-infrared probes and optogenetic tools derived from bacterial phytochromes is limited by availability of their biliverdin chromophore. To address this, we use a biliverdin reductase-A knock-out mouse model (Blvra−/−), which elevates endogenous biliverdin… read more here.
Keywords: deep tissue; optogenetic manipulation; imaging optogenetic; biliverdin reductase ... See more keywords
Signal-to-background ratio and lateral resolution in deep tissue imaging by optical coherence microscopy in the 1700 nm spectral band
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-52175-9
Abstract: We quantitatively investigated the image quality in deep tissue imaging with optical coherence microscopy (OCM) in the 1700 nm spectral band, in terms of the signal-to-background ratio (SBR) and lateral resolution. In this work, to… read more here.
Keywords: resolution; deep tissue; microscopy; tissue imaging ... See more keywords