The contribution of the locus coeruleus-norepinephrine system in the emergence of defeat-induced inflammatory priming
Sign Up to like & getrecommendations! Published in 2019 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2019.01.021
Abstract: Exposure to psychosocial stress is known to precipitate the emergence of stress related psychiatric disorders such as depression and anxiety. While mechanisms by which this occurs remain largely unclear, recent evidence points towards a causative… read more here.
Keywords: social defeat; system; defeat; stress ... See more keywords
Orexin signaling during social defeat stress influences subsequent social interaction behaviour and recognition memory
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.05.032
Abstract: &NA; Orexins are neuropeptides synthesized in the lateral hypothalamus that influence arousal, feeding, reward pathways, and the response to stress. However, the role of orexins in repeated stress is not fully characterized. Here, we examined… read more here.
Keywords: orexin; social defeat; recognition; stress ... See more keywords
Metabolite signature associated with stress susceptibility in socially defeated mice
Sign Up to like & getrecommendations! Published in 2019 at "Brain Research"
DOI: 10.1016/j.brainres.2018.12.020
Abstract: OBJECTIVE Social defeat represents a naturalistic form of conditioned fear and is often used as an animal model of depression. The present study aimed to identify the neurochemicals in select brain regions of mice exposed… read more here.
Keywords: social defeat; susceptibility; defeat stress; mice ... See more keywords
Neuropeptide Y impairs the acquisition of conditioned defeat in Syrian hamsters
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.09.049
Abstract: Recent evidence indicates that Neuropeptide Y (NPY) may function as a potent anxiolytic as well as a resilience factor that can insulate the brain from the effects of stress. However, most of these studies have… read more here.
Keywords: impairs acquisition; syrian hamsters; conditioned defeat; socially defeated ... See more keywords
Acute administration of fluoxetine increases social avoidance and risk assessment behaviors in a sex- and social stress-dependent manner in Syrian hamsters (Mesocricetus auratus)
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2022.173353
Abstract: Most studies investigating the effects of acute administration of selective serotonin reuptake inhibitors (SSRI) on responses to social stress have been conducted with males. This is despite the fact that SSRIs remain the primary pharmacotherapy… read more here.
Keywords: stress; defeat; fluoxetine; social stress ... See more keywords
Gonadal steroid hormone receptors in the medial amygdala contribute to experience-dependent changes in stress vulnerability
Sign Up to like & getrecommendations! Published in 2021 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2021.105249
Abstract: Social experience can generate neural plasticity that changes how individuals respond to stress. Winning aggressive encounters alters how animals respond to future challenges and leads to increased plasma testosterone concentrations and androgen receptor (AR) expression… read more here.
Keywords: social defeat; dependent changes; changes stress; medial amygdala ... See more keywords
Low status, humiliation, dopamine and risk of schizophrenia
Sign Up to like & getrecommendations! Published in 2023 at "Psychological Medicine"
DOI: 10.1017/s0033291722003816
Abstract: Abstract The social defeat hypothesis of schizophrenia, which proposes that the chronic experience of outsider status or subordinate position leads to increased striatal dopamine activity and thereby to increased risk, has been criticized. The aims… read more here.
Keywords: dopamine; status; low status; risk ... See more keywords
Behavioral and neurochemical effects of nociceptin/orphanin FQ receptor activation in the social defeat protocol.
Sign Up to like & getrecommendations! Published in 2022 at "Behavioral neuroscience"
DOI: 10.1037/bne0000539.supp
Abstract: The nociceptin/orphanin FQ receptor (NOP receptor) has wide expression in the nervous system and is involved in neurotransmitter release. However, the role of the NOPR in depression is not widely recognized. This study aims to… read more here.
Keywords: stress; social defeat; test; defeat ... See more keywords
Establishment of a repeated social defeat stress model in female mice
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12811-8
Abstract: Numerous studies have employed repeated social defeat stress (RSDS) to study the neurobiological mechanisms of depression in rodents. An important limitation of RSDS studies to date is that they have been conducted exclusively in male… read more here.
Keywords: social defeat; defeat stress; model; female mice ... See more keywords
The Remaining, Unconvinced Few: Using Twitter to Examine Non-CORFing Behaviors Following a Political Defeat
Sign Up to like & getrecommendations! Published in 2018 at "Communication Quarterly"
DOI: 10.1080/01463373.2017.1385498
Abstract: Twitter and other social media technologies offer social scientists new and innovative ways of investigating individual-level processes on a mass scale. The current study examined communicative behaviors associated with Cutting off Reflected Failure (CORF) in… read more here.
Keywords: unconvinced using; remaining unconvinced; examine non; twitter examine ... See more keywords
Against Normative Defeat
Sign Up to like & getrecommendations! Published in 2021 at "Mind"
DOI: 10.1093/mind/fzaa079
Abstract: Several epistemologists have advanced the idea that a subject’s epistemic status can be weakened by evidence she does not possess but should have possessed, or, alternatively, by beliefs or doubts she should have had under… read more here.
Keywords: defeat; normative defeat;