Mesenchymal Stem Cell Therapy in Chondral Defects of Knee: Current Concept Review.
Sign Up to like & getrecommendations! Published in 2020 at "Indian journal of orthopaedics"
DOI: 10.1007/s43465-020-00198-0
Abstract: Purpose Full-thickness cartilage defects if left alone would increase the risk of osteoarthritis (OA) with severe associated pain and functional disability. Articular cartilage defect may result from direct trauma or chronic degeneration. The capability of… read more here.
Keywords: defects knee; mesenchymal stem; chondral defects; cartilage ... See more keywords
Injectable cultured bone marrow derived mesenchymal cells vs chondrocytes in the treatment of chondral defects of the knee - RCT with 6 years follow-up.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of clinical orthopaedics and trauma"
DOI: 10.1016/j.jcot.2022.101845
Abstract: Articular cartilage has unique biological and biomechanical characteristics. Damage to this tissue fails to heal spontaneously, leading to progressive arthritis. Cartilage repair techniques have been looked forward to in the treatment of significant cartilage injuries.… read more here.
Keywords: bone marrow; cultured bone; treatment; marrow derived ... See more keywords
Cartiform Implantation for focal cartilage defects in the knee: A 2-year clinical and magnetic resonance imaging follow-up study.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of orthopaedics"
DOI: 10.1016/j.jor.2021.02.025
Abstract: The purpose of this study was to evaluate clinical and magnetic resonance imaging (MRI) outcomes in patients who underwent cryopreserved viable osteochondral allograft (CVOCA) implantation for focal cartilage defects in the knee at a minimum… read more here.
Keywords: magnetic resonance; study; defects knee; implantation ... See more keywords
Algorithm for Treatment of Focal Cartilage Defects of the Knee: Classic and New Procedures.
Sign Up to like & getrecommendations! Published in 2021 at "Cartilage"
DOI: 10.1177/1947603521993219
Abstract: OBJECTIVE To create a treatment algorithm for focal grade 3 or 4 cartilage defects of the knee using both classic and novel cartilage restoration techniques. DESIGN A comprehensive review of the literature was performed highlighting… read more here.
Keywords: treatment; subchondral bone; defects knee; cartilage defects ... See more keywords
Treatment of Large Cartilage Defects in the Knee by Hydrogel-Based Autologous Chondrocyte Implantation: Two-Year Results of a Prospective, Multicenter, Single-Arm Phase III Trial
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DOI: 10.1177/19476035221085146
Abstract: Objective To evaluate the clinical outcome of a hydrogel-based autologous chondrocyte implantation (ACI) for large articular cartilage defects in the knee joint. Design Prospective, multicenter, single-arm, phase III clinical trial. ACI was performed in 100… read more here.
Keywords: cartilage defects; hydrogel based; cartilage; defects knee ... See more keywords
Quadriceps Strength in Patients With Isolated Cartilage Defects of the Knee: Results of Isokinetic Strength Measurements and Their Correlation With Clinical and Functional Results
Sign Up to like & getrecommendations! Published in 2017 at "Orthopaedic Journal of Sports Medicine"
DOI: 10.1177/2325967117703726
Abstract: Background: Recent studies have found a significant deficit of maximum quadriceps strength after autologous chondrocyte implantation (ACI) of the knee. However, it is unclear whether muscular strength deficits in patients with cartilage damage exist prior… read more here.
Keywords: strength; quadriceps strength; isolated cartilage; defects knee ... See more keywords
OCA Transplantation Outcomes for Replacing Large Bipolar Defects in the Knee using Novel Techniques
Sign Up to like & getrecommendations! Published in 2017 at "Orthopaedic Journal of Sports Medicine"
DOI: 10.1177/2325967117s00238
Abstract: Objectives: Osteochondral allograft (OCA) transplantation can functionally restore large articular cartilage defects in the knee, shoulder, hip and ankle. Studies have reported 10-year survivorship between 71% and 85% and up to 74% survivorship at 15… read more here.
Keywords: bipolar defects; knee using; defects knee; transplantation ... See more keywords
Outcomes After Fresh Osteochondral Allograft Transplantation for Medium to Large Chondral Defects of the Knee
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DOI: 10.1177/2325967119832299
Abstract: Background: Articular cartilage defects of the knee can significantly impair function among young, high-demand patients. There are several techniques for chondral restoration, including osteochondral allograft transplantation (OCA), that may alleviate pain and re-create the native… read more here.
Keywords: medium large; defects knee; allograft transplantation; osteochondral allograft ... See more keywords
Biologic Augmentation for the Operative Treatment of Osteochondral Defects of the Knee: A Systematic Review
Sign Up to like & getrecommendations! Published in 2021 at "Orthopaedic Journal of Sports Medicine"
DOI: 10.1177/23259671211049756
Abstract: Background: Various surgical treatment options exist for repairing, replacing, or regenerating tissue to fill osteochondral defects. Biologic augmentation has been increasingly studied as an adjunct in the surgical treatment of osteochondral defects of the knee… read more here.
Keywords: osteochondral defects; treatment; defects knee; treatment osteochondral ... See more keywords