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   Articles with "defense peptide" as a keyword



Hydrocarbon Stapling Enables Improvement of Antimicrobial Activity and Proteolytic Stability of Host‐Defense Peptide Ocellatin‐3N

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recommendations! Published in 2025 at "ChemBioChem"

DOI: 10.1002/cbic.202500204

Abstract: Ocellatin‐3N is a cationic, amphiphilic host‐defense peptide with 19 residues, which is isolated from the Caribbean frog Leptodactylus nesiotus. Its analogue Oce‐3N‐0 shows potent inhibitory activity against both Gram‐negative and Gram‐positive pathogens, and has great… read more here.

Keywords: host defense; peptide; antimicrobial activity; defense peptide ... See more keywords

Host defense peptide Hymenochirin-1B induces lung cancer cell apoptosis and cell cycle arrest through the mitochondrial pathway.

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recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.03.029

Abstract: The antineoplastic activity of host defense peptide Hymenochirin-1B, has been extensively studied. However, the mechanism still remains unknown. In this study, linear peptide, Hymenochirin-1B, was synthesized via solid-phase peptide synthesis and evaluated for its anticancer… read more here.

Keywords: apoptosis; defense peptide; peptide hymenochirin; host defense ... See more keywords

A Designed Host Defense Peptide for the Topical Treatment of MRSA-Infected Diabetic Wounds

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recommendations! Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24032143

Abstract: Diabetes mellitus is a chronic disease characterized by metabolic dysregulation which is frequently associated with diabetic foot ulcers that result from a severely compromised innate immune system. The high levels of blood glucose characteristic of… read more here.

Keywords: defense peptide; diabetic wounds; defense; host defense ... See more keywords

Host-Defense-Peptide-Mimicking β-Peptide Polymer Acting as a Dual-Modal Antibacterial Agent by Interfering Quorum Sensing and Killing Individual Bacteria Simultaneously

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recommendations! Published in 2023 at "Research"

DOI: 10.34133/research.0051

Abstract: Host defense peptides (HDPs) are one of the potentially promising agents for infection diseases due to their broad spectrum and low resistance rate, but their clinical applications are limited by proteolytic instability, high-cost, and complicated… read more here.

Keywords: polymer; peptide mimicking; defense peptide; host defense ... See more keywords