Synergistic Activity between Two Antifungal Proteins, the Plant Defensin NaD1 and the Bovine Pancreatic Trypsin Inhibitor
Sign Up to like & getrecommendations! Published in 2017 at "mSphere"
DOI: 10.1128/msphere.00390-17
Abstract: This work describes the increased activity of a natural antifungal peptide in the presence of another antifungal peptide from a different family. This is termed antifungal synergy. Synergy is important for decreasing the amount of… read more here.
Keywords: plant defensin; plant; defensin nad1; antifungal peptide ... See more keywords
Resistance to the Plant Defensin NaD1 Features Modifications to the Cell Wall and Osmo-Regulation Pathways of Yeast
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DOI: 10.3389/fmicb.2018.01648
Abstract: Over the last few decades, the emergence of resistance to commonly used antifungal molecules has become a major barrier to effective treatment of recurrent life-threatening fungal diseases. Resistance combined with the increased incidence of fungal… read more here.
Keywords: plant defensin; plant; tolerance; defensin nad1 ... See more keywords
Immunomodulatory Effects of the Tobacco Defensin NaD1
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DOI: 10.3390/antibiotics13111101
Abstract: Background/Objectives: Defensins are important components of the innate plant immune system, exhibiting antimicrobial activity against phytopathogens, as well as against fungi pathogenic to humans. Along with antifungal activity, plant defensins are also capable of influencing… read more here.
Keywords: immunomodulatory effects; tobacco defensin; defensin; defensin nad1 ... See more keywords
Anticandidal Activity and Low Cytotoxicity of Modified Analogues of the Tobacco Defensin NaD1
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DOI: 10.3390/antibiotics14111129
Abstract: Background/Objectives: The growing resistance development among fungi, including those of Candida species, poses significant challenges to public health, emphasizing the need for the implementation of innovative therapeutic approaches. The tobacco defensin NaD1 exhibits a pronounced… read more here.
Keywords: tobacco defensin; cytotoxicity; anticandidal activity; defensin nad1 ... See more keywords