Defensin γ-thionin from Capsicum chinense improves butyrate cytotoxicity on human colon adenocarcinoma cell line Caco-2
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DOI: 10.1016/j.ejbt.2021.04.009
Abstract: Abstract Background Butyrate is a histone deacetylase inhibitor that induces apoptosis and inhibits cell proliferation of colorectal cancer cells. To improve its anticancer activity, butyrate has been evaluated mixed with drugs and different molecules. Plant… read more here.
Keywords: cytotoxicity; defensin thionin; butyrate; cell ... See more keywords
Plant Defensin γ-Thionin Induces MAPKs and Activates Histone Deacetylases in Bovine Mammary Epithelial Cells Infected With Staphylococcus aureus
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DOI: 10.3389/fvets.2020.00390
Abstract: Defensins are an important group of host defense peptides. They have immunomodulatory properties, which have been mainly described for mammal defensins, but similar effects for plant defensins remain unknown. Previously, we showed that the defensin… read more here.
Keywords: staphylococcus aureus; mammary epithelial; plant; defensin thionin ... See more keywords