Implications of Dosage Deficiencies in CTCF and Cohesin on Genome Organization, Gene Expression, and Human Neurodevelopment
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DOI: 10.3390/genes13040583
Abstract: Properly organizing DNA within the nucleus is critical to ensure normal downstream nuclear functions. CTCF and cohesin act as major architectural proteins, working in concert to generate thousands of high-intensity chromatin loops. Due to their… read more here.
Keywords: ctcf cohesin; deficiencies ctcf; gene expression;