SOCS3 deficiency-dependent autophagy repression promote the survival of early-stage myeloid-derived suppressor cells in breast cancer by activating the Wnt/mTOR pathway.
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DOI: 10.1093/jleuko/qiad020
Abstract: Early-stage myeloid-derived suppressor cells (eMDSCs) are a newly defined subset of MDSCs in breast cancer tissues, and was related to poor prognosis of breast cancer patients. Compared with classical MDSCs, eMDSCs display exceptional immunosuppressive ability… read more here.
Keywords: deficiency dependent; wnt mtor; socs3 deficiency; myeloid ... See more keywords