GW28-e0562 Irisin Deficiency Disrupts Glucose Utilization and Sensitizes the Heart to Ischemia/Reperfusion Injury
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2017.07.060
Abstract: Exercise benefits lots to prevention and prognosis of cardiovascular diseases, however, so far, the exact molecular mechanism of which mediates this process is still unknown. Exercise facilitates gene FNDC5 expression and secretes more Irisin, a… read more here.
Keywords: irisin deficiency; gw28 e0562; e0562 irisin; disrupts glucose ... See more keywords
Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1010436
Abstract: Ferroptosis is an iron-dependent form of regulated cell death associated with uncontrolled membrane lipid peroxidation and destruction. Previously, we showed that dietary dihomo-gamma-linolenic acid (DGLA; 20: 3(n-6)) triggers ferroptosis in the germ cells of the… read more here.
Keywords: lipid deficiency; ferroptosis sensitivity; deficiency disrupts; ether lipid ... See more keywords