A modified screening strategy for Lynch syndrome among MLH1-deficient CRCs: Analysis from consecutive Chinese patients in a single center
Sign Up to like & getrecommendations! Published in 2021 at "Translational Oncology"
DOI: 10.1016/j.tranon.2021.101049
Abstract: Highlights • We comprehensively analyzed both BRAF mutation status and MLH1 promoter methylation status in MLH1-deficient patients from a large consecutive CRC cohort, which may help to modify strategy of LS screening for Chinese MLH1-deficient… read more here.
Keywords: modified screening; deficient; mlh1 deficient; deficient crcs ... See more keywords
PMS2-associated Lynch syndrome: Past, present and future
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1127329
Abstract: Carriers of any pathogenic variant in one of the MMR genes (path_MMR carriers) were traditionally thought to be at comparable risk of developing a range of different malignancies, foremost colorectal cancer (CRC) and endometrial cancer.… read more here.
Keywords: lynch syndrome; deficient crcs; pms2; mmr ... See more keywords