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Published in 2022 at "Liver International"
DOI: 10.1111/liv.15384
Abstract: The tumour suppressor PTEN is a negative regulator of the PI3K/AKT signalling pathway. Liver‐specific deletion of Pten in mice results in the hyper‐activation PI3K/AKT signalling accompanied by enhanced genome duplication (polyploidization), marked lipid accumulation (steatosis)…
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Keywords:
deficient livers;
pten deficient;
steatosis;
polyploidization pten ... See more keywords