Frataxin-deficient cardiomyocytes present an altered thiol-redox state which targets actin and pyruvate dehydrogenase
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DOI: 10.1016/j.redox.2020.101520
Abstract: Friedreich ataxia (FA) is a cardioneurodegenerative disease caused by deficient frataxin expression. This mitochondrial protein has been related to iron homeostasis, energy metabolism, and oxidative stress. Previously, we set up a cardiac cellular model of… read more here.
Keywords: dehydrogenase; frataxin deficient; deficient nrvms; frataxin ... See more keywords