Articles with "deficient rats" as a keyword



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Shank3‐deficient rats exhibit degraded cortical responses to sound

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Published in 2018 at "Autism Research"

DOI: 10.1002/aur.1883

Abstract: Individuals with SHANK3 mutations have severely impaired receptive and expressive language abilities. While brain responses are known to be abnormal in these individuals, the auditory cortex response to sound has remained largely understudied. In this… read more here.

Keywords: deficient rats; shank3 deficient; auditory cortex; cortex response ... See more keywords
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Severe calcium deficiency increased visceral fat accumulation, down-regulating genes associated with fat oxidation, and increased insulin resistance while elevating serum parathyroid hormone in estrogen-deficient rats.

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Published in 2019 at "Nutrition research"

DOI: 10.1016/j.nutres.2019.09.008

Abstract: Menopause impairs calcium(Ca) metabolism and reduces bone mineral density (BMD), but the interaction of menopause with Ca deficiency in energy, glucose, lipid, and bone metabolism has not been studied. Herein we hypothesized that Ca deficiency… read more here.

Keywords: insulin; vlca; deficient rats; estrogen deficient ... See more keywords
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Uricase-deficient rats with similarly stable serum uric acid to human’s are sensitive model animals for studying hyperuricemia

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0264696

Abstract: The aim of this study was to provide a sensitive model animal for studying hyperuricemia. Male uricase-deficient rats, named Kunming-DY rats, were raised for 130 days, or orally administered with purines and other chemicals. Serum… read more here.

Keywords: deficient rats; studying hyperuricemia; uricase deficient; sensitive model ... See more keywords