Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment
Sign Up to like & getrecommendations! Published in 2021 at "Translational Psychiatry"
DOI: 10.1038/s41398-021-01381-z
Abstract: We have reported that a subpopulation of patients with schizophrenia have lower levels of vitamin B 6 (VB6) in peripheral blood than do healthy controls. In a previous study, we found that VB6 level was… read more here.
Keywords: social deficits; vb6 mice; mice; deficiency ... See more keywords
The behavioral deficits and cognitive impairment are correlated with decreased IGF-II and ERK in depressed mice induced by chronic unpredictable stress
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Neuroscience"
DOI: 10.1080/00207454.2017.1337014
Abstract: ABSTRACT Aim: To investigate the behavioral deficits, cognitive impairment and possible mechanisms induced by chronic unpredictable stress (CUS) in mice of different ages. Methods: The behaviors and cognition were tested using the open field test,… read more here.
Keywords: behavioral deficits; erk; igf erk; cognitive impairment ... See more keywords