Articles with "defined targets" as a keyword



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Tuberculosis Drug Discovery: A Decade of Hit Assessment for Defined Targets

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Published in 2021 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2021.611304

Abstract: More than two decades have elapsed since the publication of the first genome sequence of Mycobacterium tuberculosis (Mtb) which, shortly thereafter, enabled methods to determine gene essentiality in the pathogen. Despite this, target-based approaches have… read more here.

Keywords: drug discovery; decade; defined targets; tuberculosis drug ... See more keywords