Cryptic binding sites on proteins: definition, detection, and druggability
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DOI: 10.1016/j.cbpa.2018.05.003
Abstract: Many proteins in their unbound structures lack surface pockets appropriately sized for drug binding. Hence, a variety of experimental and computational tools have been developed for the identification of cryptic sites that are not evident… read more here.
Keywords: detection druggability; definition detection; cryptic binding;